Table Of Content
- Manifesting as a 6/2 Generator
- The World of Consultancy and Analysis
- An Intro to Human Design Unpacking the Profiles 6/2 Role Model/Hermit
- Here, you can find our expanded version of the Human Design 6/2 Profile! Enjoy!
- The 6/2 Role Model/Hermit Profile
- EGFR and HER2 T-BsAbs effectively treat PDAC xenografts

For a relationship to thrive, this space needs to be respected and understood. Understanding these phases helps in setting the right expectations in a relationship. Patience, understanding, and growth are key elements that partners need to focus on during each phase.
Manifesting as a 6/2 Generator
However, she says, "Their weakness is feeling that they don't want to inform. They don't want to tell other people what they're thinking or what they're wanting to do because they don't want to be controlled." There are five distinct "types" in human design (or four, depending who you ask—which we'll get into). Here's a breakdown of each, according to Brafman, Cornelius, and Stiles. The information he received then became human design, as Ra recorded his experience in a book called Rave I'Ching.
The World of Consultancy and Analysis
You work best when you’re able to manage your own time and work independently. As time goes by, during the later stages of life, the Projector focuses on and becomes a regal authority figure in their chosen field/s. This process is totally organic, and eventually, others begin to recognise the Projector’s expertise. This is an interesting combination of aura type and profile; while it can lead to much frustration early in life, later on in the second and third phases there can be enormous satisfaction. This is not correct for the 6/2, for whom the process of the first phase is to experience mistakes specifically in order to later learn and grow from them.

An Intro to Human Design Unpacking the Profiles 6/2 Role Model/Hermit
As a 6/2 Generator, your relationships can be an area where you learn significant lessons, especially during your first life phase of trial and error. Use these lessons to cultivate deeper understanding and compassion in your relationships. Understanding these challenges can provide opportunities for growth and self-understanding.
Final Reflections: Embracing Your 6/2 Generator Design
Their empathetic nature combined with the analytical skill of identifying patterns allows them to excel as therapists, counselors, and holistic health practitioners. You’re designed to be dynamic and efficient, and when you’re doing what lights you up, you can accomplish great things. You are a 6/2 Manifesting Generator, a Role Model-Hermit, and your journey is a unique and valuable one.
This doesn’t mean you have to work alone; it simply means that you should have the autonomy to manage your own tasks. As a Generator, you have a defined Sacral Center, which means you have a consistent flow of energy for work. However, it’s vital to ensure that your work is fulfilling and engaging, as this contributes to your overall satisfaction.
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This Hermit energy serves the Projector well because they will be able to wait for their invitations. In later life, the 6/2 Projector will become a leader in their area of expertise. When a 6/2 profile does not approach their life with their strategy and inner authority they will fall victim to social conditioning. Your line two energy is unconscious and is not vulnerable to conditioning. Your line two energy kicks up during this time, and you may want even more alone time than you did before. This process will end and you will be able to see your learned experience inside of your memories.
The 6/2 Role Model/Hermit Profile
The Human Design 6/2 profile combines the characteristics of the Role Model (Line 6) with those of the Hermit (Line 2), creating a unique blend of potential for universal guidance and a tendency towards solitude. Individuals with this profile are often positioned as wise mentors or guides, while simultaneously having a strong need for personal space and independence. It’s a powerful testament to your resilience, wisdom, and unique contribution to the world. Then, realize that your role model phase often involves guiding others. Share your wisdom generously and guide others from a place of authenticity.
As they move into the last phase, their vast experience combined with their innate leadership qualities positions them well for senior leadership roles. As CEOs, CTOs, or Managing Directors, their approach is often characterized by wisdom, patience, and a keen understanding of both business and people. The final phase, which accentuates their role model energy, positions them perfectly for leadership roles within educational institutions. They could become deans, headmasters, or renowned educators guiding the next generation of teachers. Given this three-phased journey, career choices for a 6/2 profile need to be flexible, allowing growth, introspection, and eventual leadership.
FACS, IHC, and ADTC analyses revealed the EGFRxHER2 T-BsAb to be nearly as effective as the superior homodimeric EGFR T-BsAb. It is again worth noting that all parental PDAC lines expressed higher levels of EGFR than HER2. However, OSCA-40 cells, which express low and comparable levels of EGFR and HER, exhibited greater sensitivities to HER2xHER2 and EGFRxHER2 T-BsAbs than to the EGFRxEGFR homodimer (Supp. Figure 5, Supp. Table 2).
EGFR and HER2 were useful targets for driving T cell infiltration and tumor ablation. Two arm Fab binding to either one or both targets was critical for robust anti-tumor effect in vivo. By engaging both targets, EGFRxHER2 heterodimeric T-BsAb exhibited potent anti-tumor effects if CDX or PDX were EGFR+HER2+ double-positive with the potential to spare single-positive normal tissue. Next up we have Projectors, who make up 20% of the world's population and offer wisdom and guidance to the rest of the world.
The NIH’s predicted 5-year survival rate for patients with pancreatic cancer is a discouraging 11.5%, a statistic that has remained largely unchanged for decades, loudly begging for more effective strategies [2]. Feature papers represent the most advanced research with significant potential for high impact in the field. A FeaturePaper should be a substantial original Article that involves several techniques or approaches, provides an outlook forfuture research directions and describes possible research applications. While there are a lot of online resources to do your own research on human design, Brafman says working with a professional can be really helpful. "A reader can translate it into more actionable items," she says, adding that every reader has a different style, so find one that's right for you.
In personal settings, individuals with the 6/2 Profile excel as mentors and role models, fostering deep connections and meaningful relationships. With their innate charisma and wisdom make them natural leaders, inspiring others to reach their full potential and embrace their authentic selves. In professional settings, 6/2 individuals thrive in leadership roles, leveraging their visionary insight and strategic acumen to drive innovation and success.
This phase is referred to as being “on the roof” because the 6/2 needs a full view of their experiences so they can learn. While you are on your roof you will have the time to heal any wounds caused by your early life. The final phase starts around the age of fifty and lasts for the rest of your life. When you “come off the roof,” it can sometimes be a cataclysmic descent. The themes of the first part of your life can come back with newfound wisdom and maturity.
As they transition to a more reflective phase, they might move into roles that require strategizing or policy-making. They could be involved in designing interventions, understanding the broader societal patterns, and crafting solutions that can have a long-term impact. The third phase of their life sees them as esteemed experts in their domain.
There is no controlling a Manifestor and attempts to do so will lead to hurt feelings. Manifestors have to learn from their personal experiences and this is even more true for those with the sixth line. Line two will bring the much-needed reflection to learn from their adventures. The final phase called the role model phase, is a time when you have tried everything, figured out what works, and are now living true to yourself.
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